MCDB 134 Lecture Notes - Lecture 1: Tobacco Mosaic Virus, Plant Pathology, Plant Virus
15 Nov 2017
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Document Summary
From the point of view of the virus: virus are pathogens that can cause a range of different diseases(affect mankind) Form point of view of the cell: to learn about the mech. Animal virus when replicate in cell, they use cell"s transcription machine. Viruses are genetically simply (~10 genes, genome ~10,000bp) compare to an animal cell (~40,000 genes) Growing virus line in lab is the rate-limiting step in the study of disease. 1918, during wwi, battle of pandemic in europe. Inhibitor will block entrance and release of influenza. Begin as a branch of pathology (study of disease) 1892, a plant pathologist - ivanovsky- found an agent that is filterable and submicroscopic in size that can be the cause of a disease. At the same time, beijerinck found that the virus isn"t only filterable but also multipliable (it multiplied only in tissues undergoing cell division)
