MCDB 21 Lecture Notes - Lecture 4: Lipid Bilayer, Microbiological Culture, Gastritis

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Viruses made up of core of nucleic acid (genome) surrounded by a layer of protein (capsid) Capsid subunits = capsomeres joined to one another like patches of a quilt to make the capsid. Envelope flexible lipid-bilayer membrane outside the capsid. Genome: dna or rna; single or double stranded. Envelope: some have envelopes & some are naked; lipid bilayer. Usually infect cells by attaching to a specific receptor. Mature inside of the host cell & lyse the cell by budding out of the cell membrane. Clinically evident illness resulting from the presence of pathogenic microbial agents, including viruses, bacteria, fungi, protozoa, multicellular parasites or prions (subliving) These pathogens are able to cause disease in animals or plants. Infectious pathologies are also called communicable diseases or transmissible diseases. Famous for isolating the bacteria that cause: 4 criteria to establish a causal relationship between a causative microbe & disease. 1) the organism is always found in diseased individuals.

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