MCDB 21 Lecture Notes - Lecture 3: Innate Immune System, Pimple, Gastritis
22 Apr 2019
School
Department
Course
Professor
Document Summary
One of the world"s most pressing public health problems. Number of bacteria resistant to antibiotics has increased since the widespread use of antibiotics. Repeated & improper use of antibiotics are primary causes for the increase in drug- resistant bacteria. Decreasing inappropriate antibiotic use is the best way to control resistance. Consequences = longer-lasting illnesses, more doctor visits/extended hospital stays & the need for more expensive + toxic medications. Physical barriers: skin, mucous, cilia in lungs. Chemical barriers: lysozymes in tears + saliva, digestive enzymes in stomach, stomach acid. Microbial barriers: phagocytes that engulf other bacteria (macrophages, dendritic cells, neutrophils), normal microflora. Inflammation: cytokines cause redness (erythema) and swelling (edema) Why we get vaccination: vaccinated with a dead pathogen so that your body. Capillaries vasodilate so white blood cells will leave your blood & go to the site of infection. Accumulation of white blood cells at infection chemicals/proteins promote inflammation histamines, cytokines, prostaglandins. Ex: pimple, gastritis, hay fever, extra mucus production.
