BICD 100 Lecture Notes - Lecture 15: Epistasis, Genetic Recombination, Gonochorism

• School: UCSD
• Department: Biol/Genetics,Cellular & Develop
• Course: BICD 100
• Professor: Keefe Reuther

Document Summary

Crispr-cas9: edited cells injected into adult human. Turned off pd-1 which slows immune response. Epistasis: one gene masks the effect of another if 2 genes affect a single trait but work together in some way, it is not epistasis: recessive epistasis, dominant epistasis, dominant suppression are epistasis. It"d (cid:271)e (cid:373)u(cid:272)h faster (cid:374)ot to ha(cid:448)e to fi(cid:374)d a (cid:373)ate. If (cid:455)ou (cid:272)lo(cid:374)e (cid:455)ourself, (cid:455)ou do(cid:374)"t ha(cid:448)e to spe(cid:374)d ti(cid:373)e, e(cid:374)erg(cid:455), a(cid:374)d risk fi(cid:374)di(cid:374)g a mate: a (cid:373)ate that (cid:455)ou"re (cid:374)ot related to: the(cid:455) ha(cid:448)e alleles that are(cid:374)"t (cid:455)our o(cid:449)(cid:374) Reduction in fitness because your offspring would only be half of: genetic and energetic cost of sexual reproduction, two-fold cost of reproduction the alleles that you have. If you have an individual that every generation has two offspring. In the case of asexual reproduction: 1 individual, then 2, then 4, then 8, then 16 (exponential population growth)