BILD 10 Lecture Notes - Lecture 4: Epigenomics, Epigenome, Folic Acid

• School: UCSD
• Department: Biology/Lower Division
• Course: BILD 10
• Professor: Michael Burg

Document Summary

Describe the classic experiment using folic acid treatment of pregnant mice and its implications for epigenomics. Describe the experiments involving nuturing vs non-nuturing mothers and how this affected the marking of genes. Briefly describe the cancer epigenetic theory and some potential epigenetic therapies that have come about (what is decitabine?) Explain how twin studies are being used to determine the epigenetic contribution to. How do the brains and dna methylation patterns differ between twin siblings;one with autism and the other without. Describe the basic studies and conclusions involving pesticide exposure to rats.