ANFS300 Lecture Notes - Lecture 3: Androgen Receptor, Y Chromosome, Testicle

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Many more males than females show the disorder. None of the offspring of an affected male exhibit the trait, but all daughters are carriers. Males carry the trait, in order to be a female they must inherit one x from dad. None of the sons of an affected male show the disorder. Have female external genitalia, blind vagina and no uterus. Testes may be present in either labia or abdomen. Syndrome results from nonfunctional androgen receptor genes. Gene on x is responsible for conferring maleness (arg) We are still trying to figure out femaleness and how it is carried out (end of lecture 1) From cell to cell within an organism. Sutton & boveri recognized that these properties parallel mendel"s heritable particles (genes) Elinor crothers --studying grasshoppers, found a non identical pair of chromosomes along with an unpaired chromosome. Follow during meiosis and found that the two patterns assort independently. Unpaired chromosome associated with chromosome that has.

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