BISC207 Lecture Notes - Lecture 4: Transfer Rna, Proline, Insulin

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BISC207 Full Course Notes
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BISC207 Full Course Notes
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Basic amino acids have a plus charge and associate with a negative charge. Dna and rna because of the phosphate. Proteins that associate with dna are called histones: histones are loaded with positively charged r groups. Have an amino end and a carboxyl end. Primary just a sequence of amino acids: simplest yet most important structure of a protein because all other structures depend on this. Secondary results from interaction of nearby amino acids: alpha helix. Each carboxyl group in the backbone forms a hydrogen bond with an amide group four residues away. To form an alpha helix the r groups get out of the way only has to do with the atoms in the backbone of the polypeptide: beta sheet. Hydrogen bonds form between carbonyl groups in one polypeptide and amide groups in a different part of the polypeptide. Adjacent strands can run in the same direction (parallel) or in opposite directions (antiparallel)

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