BISC208 Lecture 30: Unit 3 Notes

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Organization: axial skull & spine, appendicular - bones of the limbs, including the bones of the pectoral and pelvic girdles. Bones connection thru joints: compact, spongy filled with marrow, phases. Organic collagen fibrils, pro, fat, and cells. Clicker: organic phase includes different types of cells and an extracellular matrix made primarily of collagen. Clicker: material quality or fragility = relative ratio of organic/mineral. Bone-related pathology: bone pain, stree fractures/lesions, bone infections, spread of cancer to bone. 3 types of bone cells: osteoclasts (bond-degrading cells, osteoblasts (bone-forming cells, osteocytes (mechanosensors, sense changes in load-induced fluid flow, lacunar-canalicular system. Wolff law: bone tissue in a healthy person or animal will adapt to the loads it is placed under. Exercise: bone apposition, quality increased, muscle hypertrophy. Immobilization disuse/microgravity: bone loss, muscle atrophy. 2 atria, 2 ventricles e. ii. systemic = to body e. iii. pulmonary = to lungs e. iv. advantage: different pressures in 2 different systems: advantages f. i.

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