NTDT401 Lecture Notes - Lecture 4: Riboflavin, Isocitric Acid, Halloween

• School: University of Delaware
• Department: Nutrition and Dietetics
• Course: NTDT401
• Professor: Fang Richard

Document Summary

Structure of niacin pyridine ring (contains n) + carboxy or amide group. Coenzyme forms of niacin: nicotinamide adenine dinucleotide (nad, nicotinamide adenine dinucleotide phosphate (nadp) Fortified bread and bread products (rich in high protein sources) Relationship between niacin and trp can make niacin in body only if sufficient (extra) trp from diet --> occurs in liver. 60 mg trp = 1 mg niacin = 1 ne. May be bound to: complex cho --> niacytin, small peptides --> niacinogens. *both forms interfere with absorption and make niacin unavailable. Chemical treatment with lime water (base) --> only about 10% is available. Nad and nadp are hydrolyzed within gi to free nicotinamide (absorbable form) Nicotinamide (and nicotinic acid) = passive diffusion in a sodium-dependent saturable system at higher concentrations. Nad functions - oxidative reactions: glycolysis, pdh, oxidation of acetyl coa via tca cycle, b-oxidation of fa. *g3p dehydrogenase* converts g3p to 1,3 bis-p glycerate. Nadh h+ goes to etc under aerobic conditions.