BSC 2010 Lecture Notes - Lecture 5: Side Chain

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Bsc 2010- lecture 4- nucleic acids, proteins and enzymes: nucleic acids are informational macromolecules, nucleic acids are polymers specialized for storage, transmission an duse of genetics information. Nucleotides: pentose sugar, nitrogen containing base, phosphate group. Nucleosides: pentose sugar, nitrogen containing base: bases. Pyrimidines- single rings: cytosine, thymine, uracil. Purines- double rings: adenine, guanine, complementary base pairing linked by hydrogen bonds. Guanine and cytosine always pair: dna. Two polynucleotide strands from a double helix, ladder. Sugar phosphate groups form the sides of the ladder, the hydrogen-bonded bases form the rungs. Has two functions: gene expression- base sequences are copied to rna and specify amino acid sequences in proteins, replication- depends on the base pairing, proteins are polymers with important structural and metabolic roles, major functions of proteins: Genetic regulatory proteins regulate when, how and to what extent a gene is expressed: protein monomers are amino acids.

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