VPHY 3100 Lecture Notes - Lecture 1: Cytosol, Phospholipid, Lipophilicity

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Chapter 1: the study of body function (p. 4-10) The feedback mechanisms: negative feedback, common regulatory mechanism for maintenance of homeostasis, defends the set pt. Reverses the deviation produces change in opposite direction: example: insulin and blood sugar, 1. Integrating center: sensory nerve fibers, medulla oblondata of brain, motor nerve fibers, 3. 4 primary types of connective tissue: 1. Chapter 2: chemical composition of the body (p 30-32) Water as a polar solvent: water, polar (asymmetrical) solvent, tends to interact better with polar (hydrophilic) mlcs, amino acids, proteins, carbohydrates, and nucleotides are highly polar and ionized so that they are soluble in water (hydrophilic) Amphipathic molecules: contain both polar (hydrophilic) head group and non-polar (hydrophobic) tail group in their structures, soup as an amphipathic substance, rcoo-na, detergent action. Important amphipathic biomolecules: digestion of lipid bile acids (salts, transport of lipids in the blood, functions and mechanisms of the pulmonary surfactants, cell membrane structure, absorption of lipids, entry of steroids in cells.

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