BIOL 1344 Lecture Notes - Lecture 9: Descending Limb Of Loop Of Henle, Nephritis, Efferent Arteriole

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Are made of 1 million nephrons in each kidney. Corical nephrons: 85% normally used to produce urine ---> short loop of hemle. Normally used; urine concentration is 4x the plasma; concentration 1200 mmosmoles; ph 6. 0. Juxtamedullary nephrons: 15% used under stressful conditions ---> long loop of hemle. Ex) for water conservation, when a person is dehydrated. Urine conc. is 6-8x plasma; (osmolarity of plasma is 300, so jux. is 1800- Interstition has osmotic pressure outside the nephron. Efferent arteriole makes capillary bed around nephron ( in red) The capillary bed around the loop of hemle is called vasa recta. Peritubular plexus: capillary bed around papillary duct. These two terms are called counter current mechanism: urine flows in one direction, and blood flows in opposite direction. Podocytes: foot processes that wrap around the glomerular capillaries. Macula densa cells: detect the concentration of filtrate. Will control gfr depending on conc. of filtrate. Juxtaglomerular cells (jg cells): source of renin.

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