BIOL 1361 Lecture 12: Ch12 Cell Cycle

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Cell division of preexisting cells leads to new cells. Cytokinesis - division of cytoplasm into 2 daughter cells (reproductive cell) Daughters are genetically different (any cell that"s not. Genetic material copied and divided equally between 2 cells. Daughters are identical with parents hereditary material from. Cellular replication : copy dna=> separate copies => divide cytoplasm to make 2 cells. Centromere- protein fibers located in the cytoplasm which become spindle fibers during meiosis to help the cell divide. Kinetochores - structures on sister chromatids where microtubules attach. Cohesin - protein complex that regulates the separation of sister chromatids during cell division, either mitosis or meiosis. Diploid- a cell that contains 2 complete sets of chromosomes. Spindle apparatus forms (mtocs -> polar microtubules -> centrosomes containing a pair of centrioles) Microtubules attach to chromosomes at kinetochores = kinetochore microtubules. Chromosomes reach middle of spindle through microtubules pulling. Tubulin subunits get lost=kinetochore shrinks= pulls cohesions off= sister chromatids separate.

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