FSHN 426 Lecture Notes - Lecture 15: Carboxylation, Polymerization, Carnitine

• School: University of Illinois
• Department: Food Science & Human Nutrition
• Course: FSHN 426
• Professor: Y Pan

Document Summary

Week fifteen day 1 by aca on formation. Transport of acetyl coa from mitochondria to cytoplasm form precursor acetye col from pyruvate in mitochondria. Transport of citrate into the cytosol through mitochondria. 4 carboxylation of acetyl cot to malonye con. 4 initiation of synthesis with malonye cote acetyl cat. Lfa synthase catalyzes and adds to fa chain condensation, reduction, dehydration, reduction alongation by fatty acid syn those stops palmitate s forther elongation & insertion of double bonds w other entymes. I mostly inliver; regulated by acetyl con carborg ease. 47acetyl coa + 7 malonyl ca + 14 nadph = 744+(cid:10) palmitatet. Nadph is generated by recycled ofa or pentose phosphate pathway. Polymerization is the allosteric regulator that a acetyl con. Phosphorylation is the covelent regulator that & acetyl con actiu activity. Desaturation requires saturated fatty acyl con 02, enada. Lsenzymes nadh-cyto chrome b5 reductore, cytochrome 35, fatty acyl coa desaturase.