BIOLOGY 171 Lecture Notes - Lecture 29: Inner Cell Mass, Germ Layer, Cell Potency

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Animal development overview: homo sapiens fertilization: sperm meets ocyte. 1: cleavage: cell division, gastrulation: cells moving around each other, organogenesis: making organs. Fundamental developmental processes common to all animals: cell proliferation, cell movement, cell signaling, apoptosis, cell differentiation. As a normal part of development, some cells are eliminated: some cells are eliminated to protect from cancer, even if cells do not go bad, they are eliminated in development to make things work better. Di erentiation restricts alternate fates: blastocycs: clump of cell in the middle = inner cell mass zygote: fusion of sperm and ocyte. Totipotent (give rise to all cells: embryo will develop from inner cell mass, outer cells will give rise to extraembryonic tissues (like placenta) Embryonic stem cells can be derived from the inner cell mass of blastocyst. they can become any cell in the body: they are pluripotent.

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