BIOLOGY 225 Lecture 22: Lecture 11/2 - Endocrinology IV
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Need to read textbook - lecture is skeleton, but book has details. Trh, crh, gnrh, ghrh, ghih made in p. pituitary: pituitary makes gh, lh, fsh, tsh, acth, prl. Direct neuronal connection from hypothalamus neurons to pituitary. Neurons that originate in hypothalamus terminate in posterior pituitary. Neurohormones oxytocin and vasopressin synthesized in cell body and travel in vesicles down axon. Cell bodies located inside hypothalamus, directly release hormone, directly work on target tissues. **make sure to understand differences between the different orders of pathway. Vesicle moves to membrane and inserts aquaporin. Prolactin makes milk, oxytocin used for ejection of milk from breast. An experimenter places an impermeable barrier between the hypothalamus and pituitary gland to block the blood flow in the portal vein without damaging the neuronal connections in a sheep. What kind of change would you predict in the circulating levels of the following hormones. Know relationship between hypothalamus and anterior pit and posterior pit.