MCDB 427 Lecture Notes - Lecture 15: Sr Protein, Autoradiograph, Precursor Mrna

• School: U of M
• Department: Molecular, Cellular and Developmental Biology
• Course: MCDB 427
• Professor: Janine Maddock

Document Summary

Then on the c terminal region, in order to end the rna and put poly as on it, we work. There are 2 cis acting sites that are important. Poly(a) tails are not found on trna, rrna or histone mrna. They are found on heterogenous nuclear rna (hnrna) and mrna. Transcripts of eukaryotic genes extends past polyadenylation site. My notes: and is also a cleavage site. So a reoccurring theme that shows up is that transcription goes past where the mrna is going to be. )gnoring splicing, the first thing that happens is we put the (cid:887)" cap on need cis-acting sequences to say this is where you"ll cleave and this is where you"ll. Then there"s a site called the poly a site which is where the poly as will be added. There"s machinery that will cleave it to define the (cid:885)" end of the mrna. The final mrna is processed and is smaller at the (cid:885)" end.