BIOL 100 Lecture Notes - Lecture 26: Siamese Cat, Gamete, Mendelian Inheritance

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Human genetics: gene: encodes a particular protein and is always located at a specific locus, allele: a different form of a gene. Every individual gets 2 alleles for each gene. A true breeding/homozygous individual has 2 copies of the same allele. Heterozygous: when you have 2 different alleles for a given gene. Phenotype: the physical characteristic of the gene (what you see) Genotype: the genetic composition (the allele forms: pedigree: shows phenotypic segregation in several generations of related individuals. There are 3 patterns of inheritance in pedigrees. You need 2 alleles to see the effect. If neither parent has a given phenotype, but it shows up in their progeny, the trait is recessive and the parents are heterozygous. Half of the offspring of an affected person will also be affected. The phenotype appears equally in both sexes: examples: huntington"s disease. Has a late onset, you develop symptoms in 40"s and 50"s: x-linked recessive.

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