BIOLOGY 151 Lecture Notes - Lecture 7: Van Der Waals Force, Heat Shock Protein, Disulfide
Document Summary
The n terminus is the amino group of the first amino acid and the period is the carboxyl group of the last amino acid. Secondary structure- chemical and physical interactions cause folding. Characterized by a-helices and b-pleated sheets with random coiled regions. Tertiary structure- folding gives that complex 3d structure. Five factors promote protein folding and stability- h bonds, ionic bonds, hydrophobic effects, van der waals forces, disulfide bridges. When a protein is heated, it gets denatured. When cooled, it returns to normal tertiary structure, demonstrating that the info to specify protein shape is contained in its primary structure. High temp, ph changes, high concentration of polar molecules and nonpolar substances all affect the secondary and tertiary structure. Heat shock proteins are the general class of stress-induced chaperone proteins. Quarternary structure- mad of two or more polypeptides. Nucleic acids- storage, expression, and transmission of genetic info. Dna- stores genetic info coded in the sequence of their monomer building blocks.