BIOLOGY 151 Lecture Notes - Lecture 30: Genetic Testing, Epistasis, Penetrance
Document Summary
Aa x aa still likely to obtain recessive traits. Many of the alleles causing human genetic disease are recessive. Huntington disease- (know when you have it at the 40-50 age. ) If you have a parent that has a dominant trait for huntingtons disease, then you are likely to obtain it. Incomplete penetrance: individuals with a genotype correspondinh yo s trait do noy actually show the phenotype eithrr because if environmental effects or interactions with other genes. Variable expressivity: phenotyope is expressed but with a different degree of severity in different people. Benefits are personalized medicine/treatment, informed decisions about healthcare, better understanding of risks, behaviors, feeling less anxious. All of nearly all traits are influenced by many genes. Mendel studoed true breeding strains that differed with regard to only one gene. Gene interaction- a single trait is controlled by 2 or more genes, each of which has 2 or more alleles.
