CHEM 2312H Lecture Notes - Lecture 16: Reagent, Pipe Cleaner, Alkyne
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Reduce w/ sodium borohydride w/ cerium (makes sure double bond isn"t reduced) (luche reduction) the diene has very short lifetime. Figure out how much volume of it you will need (several hundred microliters)take by syringe monitor by tlc. Use hot plate to heat water, then take it off bath, then heat hexanesdangerous to heat hexanes on hot plate immediately. But don"t heat too high and too long or else will undergo reverse rxn rxn solvent = ethyl acetate. Put culture tube w/ pipe cleaner attached and don"t look @ uv light (>= 280) culture tube is made of pyrex (blocks some uv light) this is a unimolecular rxn check w/ tlc or gc. Schlenk flask, dry thf (rxn solvent), dry ipr2nh (diisopropyl amine) nbuli/hex (make sure no exposure to moisture, oxygen, and carbon dioxide. Ochem lab page 2 need equivalent of water.
