CHEN 3701 Lecture Notes - Lecture 1: Trastuzumab Emtansine, Metastasis, Biopharmaceutical

• School: UMN
• Department: Chemical Engineering
• Course: CHEN 3701
• Professor: Hackel Benjamin

Document Summary

Key challenge - cancer --> metastasis (spread of cancer) accounts for 90% of cancer deaths. Fuse antibody to drug so that it selectively targets cancer cells while leaving good cells alone. Chemical used in this kinetics - transport into body, into cell reactor designs - the molecules are expensive to make + involved a lot of r and d. Administration/pharmacokinetics-improved transport of biological molecules (want them to circulate for a long time to kill tumor, but circulating for that long can also increase side effects) If want to distribute this to whole world, should be more simple.