CHEN 3701 Lecture Notes - Lecture 5: Nitrogenous Base, Coenzyme A, Cytosine
17 Sep 2015
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Document Summary
Energy currency (usually atp; has readily available energy b/c of energy stored at ends of the phoshate bonds (@ O-)when hydrolized to adp + p, gives off deltag = -30. 5 kj/mol) Cellular signaling (signaling molecules themselves, not cofactor molecules) Components of nucleic acids (e. g. genetic info) nucleotide: covalently bonded nitrogenous base + sugar + phosphate bases. 5" - cgat - 3" nucleotides ----link----> oligonucleotide, polynucleotide. Can be chemically synthesized, which empowers genetic engineering. Chen3701_biomolecularengineering page 1 to be a metabolic cofactor look at slides for coenzyme a drawing for cellular signaling, cyclic amp. Dna encodes for the proteins (via mrna) and rna. C-g (driven by 3 hydrogen bonds) both pairs are strong enough to hold dna together, but c-g bond is a bit stronger. If look from top down view (in axial direction of the double helix) Chen3701_biomolecularengineering page 2 major groove minor groove base pairs can be separated (called denaturing)
