CHEN 3701 Lecture Notes - Lecture 14: Quadrate Bone, Paga, Opata Language
8 Oct 2015
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Noncovalent complex can include enzyme and substrate or can also include growth factor to substrate or other things too. At equilibrium, these rates are equal: association rate = dissociation rate whereas the little k"s are known as dissociation and association rate constants but we will stick to kd from chemistry. Thermodynamics for 1m basis, just dividing term in ln by 1m to make it dimensionless. Chen3701_biomolecularengineering page 1 minimal impact of t on affinity. The 2 terms in above eqn balance each other out ususally. @ high t, will have faster rates, but the association is canceled out by dissociation only for relevant t ranges though fraction bound. @ eqbm, saying @ eqbm so don"t need eq subscripts. Consider the error in this approximation looks like michaelis-menton kinetics can be specific here on semilog plot can also have table of values. Chen3701_biomolecularengineering page 3 can also have table of values.
