CHEN 3701 Lecture Notes - Lecture 28: Release Factor, Moveon.Org, Post-Translational Modification
2 Nov 2015
School
Department
Course
Professor
Document Summary
7:48 am: activation of the amino acids amino acyl - trna synthetases attach correct amino acid to trna uses the genetic code - triplet (3 nucleotides at a time encode for amino acid) Redundant (multiple codon options encode for same amino acid) 50s subunit binds initiation factors involved: elongation trna binds to the next codon in the a site. How rare is this sequence in the human genome? (we have 20 nucleotides in powerpoint) Where will the primer come? probability of matching at one site = 1/4 need to do this 20 times. Consider full genome (6 billion nucleotides) can"t just raise to 6 billion b/c might double count sites. Chen3701_biomolecularengineering page 1 we know probability of matching to the small piece of strand but what about somewhere else? for , there"s only one combo that leads to thatso you can take care of double counting.
