BIOL 205 Lecture 4: Membranes
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Document Summary
The purpose of membranes is to form boundaries between the cells or organelles and their environment. Phospholipid amphipathic lipid that composes that lipid bilayer of membranes. Some lipids, such as glycolipids, found in the plasma membrane specifically localize to the non-cytosolic half of the bilayer. Integral membrane proteins these are directly attached to the lipid bilayer and can be removed with detergents. Peripheral membrane proteins these are bound indirectly to one or the other face of the membrane. They are held in place only by interactions with other membrane proteins. They need gentler extraction methods that leave the bilayer intact. It is attached to the membrane only by one covalently attached lipid group: being a peripheral membrane protein. Detergents are amphipathic molecules that are structurally very similar to phospholipids. This disrupts the lipid bilayer and separates the proteins from most of the phospholipids.
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