ACB 8120 Lecture Notes - Lecture 73: Dural Venous Sinuses, Superior Sagittal Sinus, Choroid Plexus

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Subarachnoid space surrounding the brain and spinal cord. Into arachnoid space via median and lateral apertures. Choroid plexus = embryonic ependymal cells + vascular mesenchyme. Located in lateral, 3rd and 4th ventricles (not midbrain/mesencephalon) Blockage in the flow of csf causes buildup in ventricles (increased intracranial pressure) Could be due to narrowing of aqueduct or arachnoid villi injury. Most often caused by ruptured arterial aneurysm (arteries run in. Most often caused by head trauma - tearing of bridging veins. Shearing of the meningeal arteries in the dura mater 0 blood flows into epidural space. Protection of the brain from bloodstream chemicals and bacteria. Formed by tight junctions between the endothelial cells of brain capillaries. Water soluble molecules cannot pass at all. Makes drug treatment to the brain challenging. Note the role of astrocytes fortifying barrier. Subclavian common carotid (and) vertebral artery. Common carotid external carotid everything outside the cranium. Common carotid internal carotid everything inside the cranium.

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