ACB 8120 Lecture Notes - Lecture 40: Hexagonal Lattice, Aggrecan, Hyaluronic Acid
12 Apr 2020
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Document Summary
Cartilage: general organization of cartilage, cartilage consists of ecm, collagen fibers, 4 types, vi - attachment, x - 3d meshwork, crucial for allowing cartilage to resist compressive forces, xi - regulate size of type 2 fibrils. Ii - no fibers, not designed to resist strong tensile forces. In perichondrium (dense regular ct: form a stem cell population that divde and secrete ecm, when chondroblast becomes surrounded in its own secretions, it becomes a chrondrycyte, chrondrocytes, mature cartilage cells, mitotic in growth but limited in adults. Lining articular surfacs: respiratory tract, costal cartilages, epiphyseal plates, forming temporarty skeleton of fetus, articular, specialized hyaline that lines joint surfaces, no perichondrium, 4 zones, elastic, high elastin in ecm, higly flexible. Location: auricle of ear, auditory tubes, epiglottis of larynx. Intermediate to dense ct and hyaline cartilage: fibro, many type 1 collagen fibers and type 2, needs to resist compression and tensile, found in. Interstitial growth: cartilage can grow appositional and interstitial.
