NURS 3518 Lecture Notes - Lecture 7: Innate Immune System, Passive Immunity, Antigen Processing
Document Summary
Long-lived: ex. when your body recognizes a virus or bacteria and b and t cells respond, passive immunity: immune response caused by antibodies obtained outside of your own body (aka a fetus) - temporary, ex. Fetus"s immunity from mother: define antibody and antigen. Igg most abundant, crosses the placenta, activates complement. Igm largest, pentamer, first antibody produced in immunity, Iga dimer, in the blood and secretions. Igd found in low concentrations in the blood, antigen receptor on surface of b cells. Ige mediates allergic responses and defends against parasites: define the difference between direct and indirect antibody function. Indirect: requiring activation of other components of the innate immune response: ex: through the fc portion, antibodies activate components of innate resistance, explain the secretory immune system components and functions. including complement and phagocytes. Iga: dominant secretory immunoglobulin, prevent the attachment and invasion of pathogens through mucosal membranes, such as those of the gastrointestinal, pulmonary, and genitourinary tracts.