HSC-231 Lecture Notes - Lecture 1: Referred Pain, Bradykinin, Nociceptor
18 Jan 2018
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Document Summary
Somesthetic pathways- between neurons and brain: somatic vs visceral pain. Injured tissues release chemicals stimulate nociceptors trigger pain. Bradykinin- most potent, causes release of other chemicals, promotes healing. Convergence of projection pathways (different ways pain travels to the brain) is basis for referred pain . Referred pain- visceral (organ) pain that manifests superficially. Ex: heart attack triggers pain in shoulder or left arm. Major referred pain areas: liver and gallbladder: right neck/collarbone region, lung and diaphragm: left neck/collarbone region, heart-left chest/shouder/arm, kidney-lower abdomain, hip, upper thigh region.
