BIOL 3600 Lecture Notes - Lecture 7: Allosteric Regulation, Enzyme Inhibitor, Biological Pathway
25 Apr 2020
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#2 there are other means of enzyme regulation in addition to standard inhibition (ch. 8), the most important biologically being allostery: mm enzyme can be inhibited by 3 standard types: competitive, non-competitive, & uncompetitive, context ch. 8 enzymes play a roles in biology because life is a coordinated network of. #3 regulation (means of regulation: allostery most important biologically, covalent modification, regulatory subunits, zymogen activation, (standard inhibition) in parentheses because we already discussed this in ch. #4 biochemical pathways have committed steps regulated by allostery, usually involving feedback inhibition. Reaction that turns a b is coordinated with another reaction that turns b c and c d. Panel a) not very realistic because pathways intersect with other pathways, a network. It explains why b is the committed step: it is often irreversible, first enzyme that leads uniquely to a given product, to understand which one is the committed step in practice is to do menten-michaelis kinetics.
