PHIS 206 Lecture Notes - Lecture 1: Cell Physiology, Epithelium, Nervous Tissue

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Study of systems while they are alive: harvey motions of blood in animals, pioneer of physiology, discovered that blood circulates. Experimental, rather than observational (anatomy is observational) Sub disciplines, especially cell (= general) physiology: cell physiology assumption is that if you find out how one kind of cell does something, you know how every kind of cell does that thing. How are organs coordinated in time? (appropriate times for things to happen simultaneously in different ways) Homeostatic mechanisms = something that returns you to normal. Negative feedback - nearly universal in physiology (respond to opposite) Positive feedback usually pathological ( vicious cycles : change initiated in same direction. Disruption in homeostasis can lead to illness and death. Pathophysiology: abnormal functioning of the body associated with disease: when a homeostatic disruption becomes so severe that it is no longer compatible with survival, death results.

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