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PHPR 2813 Study Guide - Conivaptan, Tolvaptan, Plasma Osmolality

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vmturner96
7 Mar 2022
School
Lipscomb University
Department
PHPR - Pharmacy Practice
Course
PHPR 2813
Professor

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Document Summary

Starches (not used in pract will kill pt) Proteins/fld expand used in specific situations (dz-specific, refractory situation) Ns: 154 meq/l na+ / 154 meq/l cl- -&- 1/2ns: 77 na+ / 77 cl- [24hr fld intake 24hr urine output] Fluid balance is reg 1o based on serum osmolality [275-300mosm/kg; assume 1l/1kg] Concern w/ cl- content & acidosis when used in lg amts. D5/10w: used in admix; not common by itself. Plasmalyte: most similar to plasma osmolality & tonicity. Expensive; used in icu; some calorie content. Asses (1) osmolal, (2) vol status, (3) causes/eval tx. N/v; muscle cramps; coma/death in setting of high osmolal. Isotonic hyponatremia hypertonic hyponatremia in setting of normal osmolal. Due to lab error, inc tg, inc serum protein. Corrected na = na + (1. 6*(glu- causing inc in osmolality. Pulm disorders (acute resp fail, inf, +p vent) Cns disorders (acute psychosis, hemorr, inflam & demyelin dz, stroke, mass lesions, trauma)

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