PHPR 2813 Study Guide - Final Guide: Obstructive Sleep Apnea, Myotonic Dystrophy, Hypopnea

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Clinical features of osa: obesity, bmi>30 kg/m2, shortening of the mandible/maxilla, adenoid/tonsil enlargement in children and elderly, hypothyroidism, acromegaly, male gender, middle age (40-65, middle aged male population, myotonic dystrophy, ehlers danlos syndrome, smoking. Major medical issues with osa: cardiovascular and cerebrovascular events. Increased risk of stroke 40: adult form of sids, daytime sleepiness. Impaired vigilance, cognitive performance, and driving (3-6x increase in accidents: depression, disturbed sleep, hypertension, difficulty concentration, unrefreshing nocturnal sleep, nocturnal choking, nocturia, decreased libido, snoring (more a problem for partners!) Differential diagnosis of osa: narcolepsy, drugs (stimulant and sedative) How to treat osa: epworth score > 11, > 15 apnea/hypopneas per hour, similar sleepiness and 5-15/hr. Diagnosis of osa: sleep history (patient + partner, physical examination, polysomnography, cpap machine, mandibular repositioning splint (mrs) not as eff as cpap, surgery, drugs wakefulness promoting drugs (cns stimulating drugs, modafinal provigil, armodafinal nuvigil . Obstructive sleep apnea (osa: how often are you likely to doze off or fall asleep:

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