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PHPR 3813 Study Guide - Recluse Spider, Loxoscelism, Envenomation

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vmturner96
7 Mar 2022
School
Lipscomb University
Department
PHPR - Pharmacy Practice
Course
PHPR 3813
Professor

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Document Summary

Spider bites: most important info to ask: Cool, dark, undisturbed areas linens, shoes, storage areas: black widow lactrodectus. Loxoscelism: fever, chills, n/v, myalgia, morbilliform rash, hemolysis life threatening syndrome, but only 1% develop this. Dapsone: no human trials have ever shown benefit, methemoglobinemia and hemolytic anemia known. Hyaluronidase: facilitates local spread, causes erythrocyte hemolysis. Screening: dx: r/o medical differential (cellulitis, mrsa, abscess) dx of exclusion. Labs: urinalysis r/o hemolysis, cbc r/o hemolysis, dic screen, renal fxn, type and screen prn. Have to make sure not breaking down rbcs. Type and screen if start to hemolyze, start to give them blood prn, so we have to make sure hct doesn"t go <30: treatment: No abx (unless signs of infxn), supportive wound care, ice and pain medication, blood prn, plastic surgery, no antivenom. Black widow: mechanism: neurotoxic venom, may not have felt more than a pinprick sensation at.

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