PCB 3023C Lecture Notes - Lecture 29: Adult Stem Cell, Stem Cell, Cancer Cell

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Stem cells: stem cells are undifferentiated cells with the capacity for self-renewal and limitless proliferation, embryonic stem cells (es) are totipotent/ pluripotent, able to differentiate into all cell types of an organism. Adult stem cells: some adult stem cells are multipotent, able to differentiate into several different types of cells, typically closely related, while other adult stem cells are unipotent, only able to differentiate into a single type of cell. Stem cells: a stem cell can divide to form, more cells like itself or, cells that are destined to become more specialized. Stem-cell divisions can also produce two stem cells or two precursor cells, as long as the pool of stem cells is maintained. Invade and colonize territories normally reserved for other cells: cells proliferate excessively forming a tumor. Cancer and genetics: cancer is fundamentally a genetic disease, those that occur in individual somatic cells of the body as opposed to germ-line mutations, which are handed down via the.

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