Lecture : IMMUNITY-INNATE IMMUNITY-ACQUIRED IMMUNITY-ACTIVE IMMUNITY AND PASSIVE IMMUNITY

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Immunity refers to resistance of the body to pathogens and their toxic products. Innate immunity: non-specific, specific innate immunity. Acquired immunity: active acquired immunity, passive acquired immunity. Innate or natural immunity is the inborn capacity of the body to offer resistance to pathogens and their toxic products. It is due to genetic and constitutional make up of an individual. It may be specific (against a particular organism) or non-specific. Mechanisms of innate immunity: mechanical barrier against invading micro-organism is provided by the intact skin and mucosa in the body, surface secretions constitute one of the important mechanisms of innate immunity. A few examples are given below: lysozyme is found in high concentration in most tissue fluids except cerebrospinal fluid, sweat and urine. It is a mucolytic enzyme which kills micro-organisms by splitting sugars of the structural mucopeptide of their cell wall: c-reactive protein (crp). The resistance that an individual acquires during his life(cid:2)time is known as acquired immunity.

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