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BIBB 270 Study Guide - Midterm Guide: Monoamine Oxidase, Adenylyl Cyclase, Adrenal Medulla

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kitcat
7 Nov 2022
School
UPenn
Department
Biological Basis of Behavior
Course
BIBB 270
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Document Summary

Vmat 1 (adrenal medulla) & vmat 2 (brain) Auto receptors - gpcrs - d2 subtype - -ve feedback. Somatodendritic: open k+ channels - flow out - firing rate. Terminal: i- da synthesis + release, > 1 of : open k+ channels - i- vgccs ca2+ entry - reuptake (dat) - i- Auto receptors - gpcrs - 2 subtype - -ve feedback. Somatodendritic - open k+ channels - flow out - firing rate. D1 & d5 - s+ ac via gs. D2, d3 & d5 - i- ac via gi, k+ channel opening. 1 - ca2+ & pkg via gq. 2 - i- ac via gi & k+ channel opening ( affinity in pfc) 5ht1a - forebrain (postsynaptic) & raphe nuclei - brainstem (autoreceptors) - camp by i- ac & . 5ht2a - cortex, striatum & na - plc 2nd messenger system via gq - ca2+ Mesolimbic da pathway - vta na - motivated behaviours & +ve schizophrenia symptoms.

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Related Questions

Serotonin, norepinephrine, and dopamine are a group of neurotransmitters collectively called monoamines. A lack of these monoamines has been linked to depression. Depression is treated with drugs that prolong the effect of these neurotransmitters either by preventing the re-uptake of the neurotransmitters, or by inhibiting the enzyme that breaks down these neurotransmitters.

Which of the following statements about neurotransmitters are true? The table lists the classifications of three antidepressants.

Antidepressant Classification
fluoxetine selective serotonin re-uptake inhibitor (SSRI)
phenelzine monoamine oxidase (MAO) inhibitor
amitriptyline tricyclic antidepressant

Check all that apply.

View Available Hint(s)

Check all that apply.

Depression may be treated with monoamine agonists.
Some drug addictions are the result of dopamine agonists.
A deficiency of serotonin, norepinephrine, and dopamine is associated with depression.
MAO inhibitors are examples of monoamine antagonists.
Fluoxetine inhibits the enzyme that breaks down monoamines.
Dopamine plays a role in feelings of pleasure and pain.
Amitriptyline and fluoxetine both prevent the re-uptake of serotonin and norepinephrine.

why do antidepressants affect mostly norepinephrine and serotonin, but not dopamine?

Quais são os principais neurotransmissores excitatórios?

a) Acetilcolina, norepinefrina, epinefrina, dopamina, glutamato e serotonina.
b) Acetilcolina, glicina e ácido -aminobutírico.
c) Acetilcolina, dopamina, glutamato e serotonina.
d) Acetilcolina, norepinefrina, glicina e ácido -aminobutírico.
e) Acetilcolina, norepinefrina, epinefrina, ácido -aminobutírico, glutamato e serotonina.