NFS 411 Lecture Notes - Calcium Hydroxide, Osteolysis, Bone Marrow
4 Feb 2023
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Osteocytes (bone cells) within the lacunae organized around blood vessels. Canaliculi: form pathways for blood vessels, exchange nutrients and wastes, minerals, two thirds of bone matrix is calcium phosphate i. Reacts with calcium hydroxide: forms crystals of hydroxyapatite, which incorporates other calcium salts and iron, bone cells, make up only 2% of bone mass, bone contains four types of cells i. Osteocytes: mature bone cells that maintain the bone matrix, to maintain protein and mineral content of matric ii. Osteoblasts iii. iv: bone building cells, promote osteogenesis. Osteoprogenitor cells: mesenchymal stem cells that divide to produce osteoblasts. Osteoclasts: secrete acids and protein-digesting enzymes, disinvestment bone matrix and release stored minerals (osteolysis, bone killing cells, bone formation and growth, osteogenesis i. Human bones grow until about age 25: ossification i. The process of replacing other tissues with bone: calcification i. ii. Occurs during bone ossification and in other tissues: ossification i. ii.
