NFS 485 Lecture Notes - Hyperpigmentation, Itch, Erythema

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Usually happens after the cancer has spread: fatigue, may be early and may not be obvious, pain, means it has metastasized, skin changes i. ii. iii. iv. v. Unrestrained proliferation of cells i. ii. iii. iv. v: carcinogens i. Chemicals and other substances that can cause cancer: major categories of genes that influence cancer i. ii. Oncogenes: exert effect tumor growth by controlling cell division. Tumor-suppressor genes: cause apoptosis but may lose function if mutated, epigenetics i. Study of changes in gene activity that are not caused by changes in dna sequence: chromatin i. The complex of dna and proteins, histones, in the nucleus of the cell: nutritional genomics i. ii. Study of genetic variations that cause different phenotypic responses to diet. Risk factors: heavy consumption of red meat, food preparations methods: smoking, salting, and pickling foods, high temperature cooking of red meats.

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