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15 Jul 2019

Please answer this question in regards to the hormone insulin

What organ/tissue releases the hormone?

What causes the hormone to be released?

What organs/tissues are affected by the hormone?

How does the hormone interact with its target tissue â does it bind to a receptor(discuss the receptor)? Is it brought into the cell (how? Where does it go?)?

What reactions occur in the cell after the hormone binds/is brought in?

What is the effect in the body after the hormone acts?

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Irving HeathcoteLv2

18 Jul 2019

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Related questions

Key: A.Increase

B.Decrease

C. Remain thesame

For questions 19-20 use the following information Thyroid-stimulating hormone (TSH) is secreted from the anterior pituitarygland and acts on the thyroid gland to increase the secretion ofthyroid hormones. Thyroid hormones, on the other hand, have anegative-feedback effect on TSH secretion (See Fig. 16.8 in yourtext). For a person having normal thyroid function, the rate atwhich TSH and thyroid hormones are secreted remains within a normalrange of concentrations. In some people, however, the immune systembegins to produce an abnormal substance that functions likeTSH.

Predict what that substance will do to:

19. _____the rate of thyroid stimulating hormone secretion

20. _____ the rate of thyroid hormone secretion.

For question 21 use the following information. Background:Hormones are dissolved in blood plasma and transported either in afree form or bound to plasma proteins. Hormones that are lipidsoluble, such as steroids and thyroid hormone, circulate in theblood in combination with these plasma proteins. Hormones that bindto plasma proteins do so in a reversible fashion according to theequation:

H + BP <-----------> HBP

(Hormone) (BindingProtein) (Hormone bound to binding protein)

An equilibrium is established between the free plasma proteinsand the hormones bound to the plasma proteins. This equilibrium isimportant because only a free hormone is able to diffuse throughcapillary walls and bind to target cells. The combination of ahormone bound to a binding protein reduces the rate at which theydiffuse through the walls of capillaries.

This increases the half-life of the hormone. The half-life isthe length of time it takes to eliminate half a dose of a substancefrom the circulatory system. The half-life of a hormone is astandard measurement used by endocrinologists because it allowsthem to predict the rate at which a given hormone will beeliminated from the body.

21. _____How is the half-life of a hormone affected by adecrease in the concentration of the

specific plasma protein to whichthat hormone binds? Remember if the time to

eliminate a hormone from theblood stream is longer then the half life has increased.

If the time to eliminate ahormone shortens then the half life has decreased

22. _____Consider a hormone that is secreted in large amounts ata given interval, modified

chemically by the liver, andexcreted by the kidney at a rapid rate, making the

half-life of the hormone in thecirculatory system very short. The hormone therefore

rapidly increases in the bloodand then decreases rapidly. Predict the

consequences of liver and kidneydisease on the blood levels of that hormone.

For question 23 use the following background information:Periodic increases in the sensitivity of some tissues to certainhormones is called up-regulation. It results from an increase inthe rate of receptor molecule synthesis. In many tissues the numberof hormone receptors rapidly decreases after exposure to certainhormones. This is called down-regulation.

Problem. Estrogen is a hormone secreted by theovary. It is secreted in greater amounts after menstruation and afew days before ovulation. Among its many effects is causing

up-regulation of receptors in the uterus for another hormonesecreted by the ovary called progesterone. Progesterone is secretedafter ovulation. A major effect of progesterone is to cause theuterus to become ready for the embryo to attach to its wallfollowing ovulation. Pregnancy cannot occur unless the embryoattaches to the wall of the uterus.

23. ______Predict the consequences on becoming pregnant if theovary secretes too little

estrogen?

24. ______ Predict the effect of inadequate dietary intake ofcalcium on PTH secretion

25. ______ Predict the effect of inadequate dietary intake ofcalcium on Calcitriol secretion

violetspider457

Which of the following is notone of the effects of muscle-building anabolic steroids?

A.	Cessation of menstrual periods in women
B.	Increased body and facial hair in women
C.	Reduced risk of cancer and heart disease in men
D.	Breast tissue diminution in women
E.	Kidney disease

Which of the following statementsabout hormones is true?

A.	The same hormone can cause different responses in differenttypes of cells.
B.	Whenever a hormone encounters a cell with a unbound receptor towhich it can bind, it can bind.
C.	The receptor for a hormone may be on the secreting cellitself.
D.	The receptor for a hormone may be in the plasma membrane orinside the cell.
E.	All of the above

Which of Wigglesworth's observationsof Rhodnius bugs helped explain the role of insecthormones?

A.	A blood meal triggers molting in these bugs.
B.	If decapitated immediately following a blood meal, the bug willmolt.
C.	When two bugs are connected, they molt simultaneously.
D.	When two bugs are connected, the feeding status of one cantrigger molting in the other.
E.	When two bugs are decapitated and connected, they do not moltinto adults.

Steroid hormones

A.	must bind to carrier proteins to be transported in the blood totheir target cells.
B.	bind with receptor proteins in the plasma membrane.
C.	are synthesized from epinephrine in the adrenal gland.
D.	are released from the cells that make them by exocytosis.
E.	are mostly derivatives of the amino acid tyrosine.

Which of the following is notone of the distinct chemical groups to which hormones belong?

A.	Steroids
B.	Proteins
C.	Peptides
D.	Carbohydrates
E.	Amines

Which of the following hormones isnot paired correctly with its target organ?

Oxytocin

turquoiseporpoise808

QUESTION 1

Which of the following is an example of an extracellular signal molecule?

	a.	IP₃
	b.	cAMP
	c.	Insulin
	d.	Diacylglycerol

2 points

QUESTION 2

Nuclear hormone receptors _____

	a.	Bind to water soluble ligands
	b.	Activate second messengers
	c.	Regulate transcription in response to ligand binding
	d.	Are normally located on the plasma membrane

2 points

QUESTION 3

Which of the following does not occur when a receptor tyrosine kinase is bound by ligand?

	a.	Phosphorylation of the RTK
	b.	Cytoplasmic proteins bind the phosphorylated RTK
	c.	Dimerization of the RTK
	d.	The RTK binds to DNA to regulate transcription

2 points

QUESTION 4

Which of these is a logical signal-transduction pathway?

	a.	An intracellular receptor activates phospholipase C, which cleaves a membrane protein to form IP₃, which then activates the opening of an ER channel protein, which releases cyclic AMP into the cytoplasm, where it binds to an intracellular enzyme that carries out a response.
	b.	A G-protein-linked receptor activates G protein, which activates phospholipase C, which cleaves a membrane lipid to form IP₃, which binds to a calcium channel on the ER, which opens to release calcium ions into the cytoplasm, which bind to an intracellular enzyme that carries out a response.
	c.	An ion-channel receptor opens, allowing a steroid hormone to enter the cell; the steroid hormone then activates protein kinases that convert GTP to GDP, which binds to an intracellular enzyme that carries out a response.
	d.	A tyrosine-kinase receptor activates adenylyl cyclase, which activates phospholipase C, which converts ATP into cyclic AMP, which binds to an intracellular enzyme that carries out a response.

2 points

QUESTION 5

Which of the following is an example of signal amplification?

	a.	activation of an enzyme molecule
	b.	activation of a specific gene by a growth factor
	c.	Breakdown of many cAMP molecules
	d.	activation of 100 molecules by a single signal binding event

2 points

QUESTION 6

Consider a signal transduction pathway that utilizes cAMP as a second messenger to activate PKA (Protein Kinase A). Which of the following situations will result in the cellular response?

		The G protein releases GDP and binds to GTP
		The target protein (adenylyl cyclase) is inactive
		The regulatory subunits of PKA (Protein Kinase A) are bound to the catalytic subunits
		The appropriate G protein is bound to GDP

2 points

QUESTION 7

Which of the following is found in only some signal transduction pathways? [In other words, which is not found in all signal transduction pathways?]

		Receptor protein
		Extracellular signal molecule
		Intracellular signaling molecule
		Cellular response
		Effector protein

2 points

QUESTION 8

The enzyme that specifically catalyzes the conversion of ATP to cAMP is:

		Adenylyl phosphatase
		Adenylyl kinase
		Adenylyl dehydrogenase
		Adenylyl cyclase

2 points

QUESTION 9

If an animal cell suddenly lost the ability to produce GTP, what might happen to its signaling system?

		It would use ATP instead of GTP to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
		It would not be able to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
		It would employ a transduction pathway directly from an external messenger.
		It would be able to carry out reception and transduction but would not be able to respond to a signal.

2 points

QUESTION 10

A hormone signal is sent from the brain to other parts of the body via the bloodstream. Why do only certain cells respond to this signal?

		Hormones do not last long enough in the bloodstream to stimulate a cellular response
		Only cells that have a specific transcription factor gene will be able to respond to the signal
		Only cells in the immediate vicinity of the cell sending the signal will respond
		Only cells that have a receptor for the specific signal will be able to respond to it