Which of the following is FALSE about ribose and nucleotide and nucleic acid synthesis?
a) Ribose can be synthesized in virtually all tissues
b) Since ribose is not a significant constituent of systemic blood,tissues must satisfy their own requirement for this important precursor of nucleotides.
c) It is necessary to have a completely functioning pentose phosphate pathway for a tissue to synthesize ribose phosphates.
d) The pentose phosphate pathway provides ribose residues for nucleotide and nucleic acid synthesis.
e) Although muscle tissue contains only very small amounts of glucose-6- phosphate dehydrogenase and 6-phosphogluconate dehydrogenase, it is capable, like most other tissues, of synthesizing ribose 5-phosphate for nucleotide synthesis by a reversal of the nonoxidative phase of the pentose phosphate pathway utilizing fructose 6-phosphate.
Which of the following is FALSE about ribose and nucleotide and nucleic acid synthesis?
a) Ribose can be synthesized in virtually all tissues
b) Since ribose is not a significant constituent of systemic blood,tissues must satisfy their own requirement for this important precursor of nucleotides.
c) It is necessary to have a completely functioning pentose phosphate pathway for a tissue to synthesize ribose phosphates.
d) The pentose phosphate pathway provides ribose residues for nucleotide and nucleic acid synthesis.
e) Although muscle tissue contains only very small amounts of glucose-6- phosphate dehydrogenase and 6-phosphogluconate dehydrogenase, it is capable, like most other tissues, of synthesizing ribose 5-phosphate for nucleotide synthesis by a reversal of the nonoxidative phase of the pentose phosphate pathway utilizing fructose 6-phosphate.
