14). During the early 1700âs, a small group of pacifist Protestants fled Germany to avoid religious persecution. This group, the Dunkers, settled in the farmland of eastern Pennsylvania and has been relatively isolated from other groups of people living in the area (they have strict rules about marriage outside of the group). The original group was comprised of 50 families.
The current Dunker population is genetically distinct from the rest of the United States (and modern Germany) in terms of the ABO blood group system. In the Dunker population, the frequency of the IA allele is .30 (30%) and the frequency of the O blood type is .16 (16%). In the general US and German population the frequency of the IA allele is .40 and the frequency of the O blood type is .25 (25%).
a). What are the frequencies of the IB and i alleles in both populations? Show your work.
b). Use your knowledge of the founder effect to explain the differences in ABO blood group allele frequencies between the 2 populations and indicate whether or not this is an example of adaptive evolution.
14). During the early 1700âs, a small group of pacifist Protestants fled Germany to avoid religious persecution. This group, the Dunkers, settled in the farmland of eastern Pennsylvania and has been relatively isolated from other groups of people living in the area (they have strict rules about marriage outside of the group). The original group was comprised of 50 families.
The current Dunker population is genetically distinct from the rest of the United States (and modern Germany) in terms of the ABO blood group system. In the Dunker population, the frequency of the IA allele is .30 (30%) and the frequency of the O blood type is .16 (16%). In the general US and German population the frequency of the IA allele is .40 and the frequency of the O blood type is .25 (25%).
a). What are the frequencies of the IB and i alleles in both populations? Show your work.
b). Use your knowledge of the founder effect to explain the differences in ABO blood group allele frequencies between the 2 populations and indicate whether or not this is an example of adaptive evolution.
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Related questions
Problem A: Shipwreck Founder Effect Genetics
In the year 1782, a small passenger schooner (the HMS Leaky) was blown off course, crashing into the rocks of a then-uncharted mid-Atlantic island. The 30 survivors built shelter and found plentiful food on the island. Within a year, it was clear that there was little chance of rescue and no means of leaving. Soon, the warm tropical nights led couples to succumb to the romantic tendencies that moonlight walks on the beach can induce. Before long, babies were born, and the ânewâ civilization of the island now known as Gilligania was off to the races.
A genetic analysis of the remains of those original islanders showed the following ABO blood type phenotypes:
| Blood Type | Number of People |
| A* | 9 |
| B** | 7 |
| AB | 4 |
| O | 10 |
*Four heterozygotes (iA iO) and five homozygotes for iA
** Five heterozygotes (iB iO) and two homozygotes for iB
Keep in mind that the blood type alleles iA and iB are codominant over each other, and that the iO allele is recessive to both iA and iB. If you need to do so, review the genetics of this system in Campbellâs Biology. Based on this information, please answer the following questions (show your work):
1. What were the frequencies of the three alleles in the original survivor population on the island?
2. Determine the genetic structure (allele and genotype/phenotype frequencies) for this gene system in the island population in 1932, when the island was ârediscoveredâ by cartographers. The population at that time had grown to 185 people.
THis was all the information we were given
