The permeability of a lipid bilayer for glucose is 10-8 cm/sec. Consider a cell whose glucose transporter is knocked out. If it is placed in a solution that contains 1 mM glucose, how many glucose molecules will enter the cell in 10 seconds? Assume that the cell contains no glucose and the surface area of its plasma membrane is 5 μm2.
Please give a thorough explanation.
The permeability of a lipid bilayer for glucose is 10-8 cm/sec. Consider a cell whose glucose transporter is knocked out. If it is placed in a solution that contains 1 mM glucose, how many glucose molecules will enter the cell in 10 seconds? Assume that the cell contains no glucose and the surface area of its plasma membrane is 5 μm2.
Please give a thorough explanation.
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Please answer te following cell biology questions:
1.) Here's one experimental approach to finding out how rapidly a membrane transporter can move its solute into the cell: combine biochemical information about how much solute accumulates in the cell over time with structural information about how many transporters are on the surface of the cell. You are studying a spherical eukaryotic cell that has a diameter of 17 μm and is engaged in glycolysis. Its energy source is glucose, which it is taking up from its environment via Na/glucose symporters distributed throughout the surface of its plasma membrane. By briefly adding an inhibitor of all glucose breakdown, you are able to determine that glucose accumulates in the cell at the rate of 48 μM/hr.
What is the flux of glucose into the cells (flux is expressed in moles per cm2 per sec)?
Answer: ______mol/(s â cm)2
| 2.) If electron microscopy indicates that there is on average 1 Na/glucose symporter per μm2 of the plasma membrane, at what rate must each symporter transport glucose, in molecules per second? |
Answer: ________molecules/s
