Question

Question 1 10 pts

What three kinds of cells are infected by HIV?

macrophages, T-Helper cells and dendritic cells

B-cells, skin cells and T-helper cells

B-cells, T-Helper cells and T-killer cells

macrophages, dendritic cells and cytotoxic T-cells

Question 2 10 pts

Sometimes an HIV infected cell is not killed immediately after infection, but lives on, and continues to be a source of the infection for the lifetime of the patient. What is the mechanism that allows the HIV virus to remain in the cell, to get passed down to all descendants of that cell, and to retain the ability to be reactivated for the lifetime of the patient?

Question 3 10 pts

List the three processes that viruses are dependent on their host cells for.

1.

2.

3.

Question 4 10 pts

What does the ELISA test for HIV infection measure?

HIV-specific antibodies

Hepatitis B-specific antibodies

circulating HIV particles

HIV-specific DNA

Question 5 10 pts

What is the cell surface receptor for HIV?

CD4

CD8

MHCII

HIV

Question 6 10 pts

What is the likely origin of HIV-1?

infection of humans by a simian virus native to the chimpanzee

germ warfare research by the CIA

sexually transmitted to humans through relations with sheep

a new human-chimpanzee hybrid virus accidentally made in a laboratory with recombinant DNA

Question 7 10 pts

How does AZT block the production of infectious virus?

It acts as a substitute for a DNA nucleotide that can only be inserted by the viral reverse transcriptase. The presence of the AZT in the DNA aborts the production of new viral DNA.

It directly blocks the reverse transcriptase.

It blocks the protease that cuts apart the three viral proteins, which is a necessary step during viral synthesis.

It blocks the adsorption of the virus to the CXCR4 and CCR5 receptors on the T-cell surface.

Question 8 10 pts

How do protease inhibitors work?

It blocks the protease that cuts apart the three viral proteins, which is a necessary step during viral synthesis.

It directly blocks the reverse transcriptase.

It acts as a substitute for a DNA nucleotide that can only be inserted by the viral reverse transcriptase. The presence of the AZT in the DNA aborts the production of new viral DNA.

It blocks the adsorption of the virus to the CXCR4 and CCR5 receptors on the T-cell surface.

Question 9 10 pts

What are the 2 most common causes of a false negative result in the HIV test?

1.

2.

Questions 10-13

The next set of 4 questions deal with the possible ways that a virus, not necessarily the HIV, can enter the body. Answer TRUE or FALSE to each question.

Question 10 2.5 pts

Some viruses can enter the body through breaks in the skin.

True

False

Question 11 2.5 pts

Some viruses can enter the body through the anal/genital tract.

True

False

Question 12 2.5 pts

Some viruses can enter the body through the oral cavity and the digestive tract.

True

False

Question 13 2.5 pts

Some viruses can enter the body through inhalation via the respiratory tract.

True

False