Can someone please help me figure this out? We have to figure out an experiment to get at least 90% yield of compound B.
These are the topics covered that we can use to plan this experiment:
1) Basic Operations: Using a weighing balance; Separation, Density. 2)Separating the Components of Panacetin - Acid-Base Reactions, Stoichiometry Techniques: Separation, extractions 3) Identifying the Constituents of Panacetin: Key techniques: Recrystallization and Melting point 4)Synthesis of Salicylic acid . Key techniques: Reflux, Recrystallization, Melting point 5) Separation of Unknown by Chromatography-Concepts: Polarity, capillary action, Technique: Column and Thin layer chromatography 6)Dehydration of cyclohexanol to an cycloalkene. Key Concepts: Preparation, and Reactions Hydration, Halogenation & Hydro halogenation of Alkenes; 7)Polarimetric Analysis of Unknown Sugars. Key concepts: Stereochemistry Techniques: Optical rotation 8)Properties of organic compounds -Concepts: Solubility, Hydrogen bonding; Technique: Distillation 9)Preparation of 2-chloro-2-methylbutaneâAn Sn1 reaction - Key concepts: Nucleophilic Substitution reactions
Lab 10: Fall 2017-Planning an Organic chemistry lab experiment 18 points Due Week of Nov 27 before start of Lab final exam Name: Problem 1: Using any technique and chemical reaction(s) covered in CHE 201 this semester prepare compound B from 5 Cl mmoles of compound A. Compound A is very expensive and your planned reaction needs to be efficient (90 % or higher yield). PART A: 13 points (replaces data sheet, note book, performance and lab report points) 1. Plan and show your planned synthetic scheme in the Properties Mol. weight form of a reaction equation. 3 points Provide a detailed procedure (Preparation, Purification & Analysis). 10 points 1. Procedure should include quantities (with correct 178.2 94 C 348 C 0.02 196.6 166 C 377 C 0.5 214.1 194 C 488 C 0.8 2. Melting/Freezing Point Boiling Point stoichiometry) of chemicals required. Mention all the techniques that will be required. 10 ml hot water) Solubility (grams in 3. Name all the glassware required. 4. Provide a data table, it should list all the reagents Solubility (grams in 10 ml hexane) 0.8 0.4 0.44 and the required quantities needed for the preparation and purification. Solubility (grams in 10 ml ethyl ether) 0.8 0.5 5. Provide a flowchart for the planned synthesis. PART B: 5 points (replaces pre-lab quiz 10) Using curved arrows to designate the flow of electrons, provide a detailed stepwise mechanism for your planned reaction(s) Complete worksheet Attach more sheets of paper as needed 11/10/2017
