IMED2003 Study Guide - Midterm Guide: National Health And Medical Research Council, Clinical Trial, Cohort Study

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Evidence from systematic review of relevant randomised controlled trials (rct) Iii-2 evidence from comparative studies non-rcts, cohort studies, case-control studies (but have controls) Iii-3 evidence from comparative studies non-rcts, cohort studies, case-control studies (but have controls) In accordance with their views on the interpretation of research data. There is agreement that there should be room for debate regarding the individual merit of different research designs. Others have challenged having systematic reviews and meta-analyses at the top of the pyramid at all. Because heterogeneity (clinical, methodological, statistical) can"t be eliminated. Because it is not uncommon for different meta-analyses on the same topic to have conflicting results. Because they are frequently conducted by people without sufficient expertise, many are of doubtful quality. Rct > cohort > case control > case series. Rct > cohort > case control > case series cohort study > case control > case series.