IMED2004 Study Guide - Final Guide: Mendelian Inheritance, Gamete, Meiosis
Document Summary
Understand and be able to define: linkage. Outputs of recombination given parental input types. Be able to describe that linked genes do not assort independently. Understand the process of meiotic recombination and how to assess non-recombinants and recombinants. Be able to define and calculate recombination frequencies. Understand how linked and unlinked genes differ in the above. Be able to calculate outcomes of crosses with linked genes. As chromosomes separate into different gametes during meiosis, the two different alleles for a particular gene also segregate so that each gamete acquires one of the two alleles. Cells contain 2 copies (alleles) of each gene. Gametes carry only one copy of each gene (random) Important in linkage which is next step after segregation. Alleles separate through meiosis during formation of gametes. = gametes carry 1 copy of each gene. Each gametes has equal chance of obtaining either member of each gene pair (allele)
