IMED2004 Study Guide - Final Guide: Egg Cell, Cell Division, Wild Type
Document Summary
Mutation in a cell that produces gametes. Cell division that produces reproductive cells in sexually reproducing organisms. Results in four daughter cells each with half the number of chromosomes of the parent cell, as in the production of gametes and plant spores. Occur in germ cells (sperm or ova) And can be passed to one"s children at conception. All cells of embryo will be heterozygous mtwt . Gametes will either be mt or wt . Nonsense mutation: can give shorter protein or non functional protein at all. If you have it you have the disorder. If a parent passes it the parent must have the disorder. Dominant diseases are single gene disorders that occur in the heterozygous state. When an individual has one mutant copy of the relevant gene and one healthy copy. For a given single gene dominant disorder, expect: Heterozygous mutations inherited from affected parent, or de novo.
