BIOL 371 Study Guide - Midterm Guide: Gc-Content, Noncoding Dna, Sanger Sequencing
Document Summary
A functional orf is one that actually encodes a protein and can be identified from a computer search of the sequence. Uncharacterized (or unknown) orfs are said to encode hypothetical proteins. Many noncoding regulatory rna molecules are conserved only in their 3d structure, with little sequence homology. Which is likely to have more genes, a species of bacteria with 8 mbp of dna or a eukaryote with. The bacteria would likely have more genes since there is a large correlation between genome size and orfs in prokaryotes. The larger the genome, the more genes there are for transcriptional regulation and signal transduction. Genesthat are related in sequence due to shared evolutionary ancestry. Genes whose similarity is the result of gene duplication at some time in the evolution of an organism are called paralogs. Genes found in one organism that are similar to genes in another organisms because of descent from a common ancestor are called orthologs.
